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WARNING: Do NOT combine with any other paracetamol or ibuprofen containing medicines. Do not exceed the daily recommended dose.

2 tablets of MAXIGESIC^® 4 times per day provides more effective pain relief than paracetamol 4000mg per day or ibuprofen 1200mg per day given in 4 divided doses. Claim based on trials of post-operative pain relief after removal of 1-4 wisdom teeth^1,2

Ref 1. Merry et al (2010). “Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial” British Journal of Anaesthesia 104(1): 80-88. Result achieved in a trial of post-operative pain relief after removal of 1-4 wisdom teeth using 2 tablets MAXIGESIC^® compared with paracetamol 1000mg or ibuprofen 300mg alone 4 times a day (paracetamol 4000mg or ibuprofen 1200mg per day). Results assessed on the Intention-to-treat (ITT) patient population, including data following the use of rescue medication. Research sponsored by AFT Pharmaceuticals.

Ref 2. Daniels et al (2018). “Analgesic Efficacy of an Acetaminophen/ibuprofen Fixed- dose Combination in Moderate to Severe Postoperative Dental Pain: A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial”, Clinical Therapeutics 40 (10): 1765-1776. Result achieved in a trial of post-operative pain relief after removal of at least 2 wisdom teeth using MAXIGESIC^® (paracetamol 975mg/ibuprofen 292.5mg) compared with paracetamol 975mg or ibuprofen 292.5mg alone 4 times a day (paracetamol 3900mg or ibuprofen 1170mg per day). Study results assessed on the intent-to-treat (ITT) population with adjustment for the use of rescue medication. MAXIGESIC^® 975/292.5mg US combination is bioequivalent in fed/non-fasting conditions to MAXIGESIC^® 1000/300mg NZ combination at full dose (Aitken et al., J Bioequiv Availab 2018, 10:5). Research sponsored by AFT Pharmaceuticals.

MAXIGESIC^® film coated tablets are for the temporary relief of pain, the reduction of fever and the discomfort associated with fever. Do not use if you have asthma or a stomach ulcer. Do not use in children under 12 years or if you have kidney disease. Always read the label. Use only as directed. Incorrect use can be harmful. If symptoms persist consult your healthcare professional. AFT Pharmaceuticals, Auckland. TAPS PP9486. NZ Patent No. 552181.

MAXIGESIC PE^® film coated tablets are for the temporary relief of cold and flu symptoms including headache, fever, pain and nasal congestion. Do not use if you have asthma or a stomach ulcer. Do not use in children under 12 years or if you have kidney disease. Always read the label. Use only as directed. Incorrect use can be harmful. If symptoms persist consult your healthcare professional. AFT Pharmaceuticals, Auckland. NZ Patent numbers 613918 and 617848.

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